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Vitamin D
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Vitamin D (Cholecalciferol)

Integrated Medicine

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Vitamin D, otherwise known as the sunshine vitamin, is significant in normal body growth and development. In particularly, vitamin D is used to absorb calcium and phosphorus to create bone. Great sources of this supplement include fortified milk, oily fish, liver, and eggs.

How This Vitamin Works in Your Body:
Absorbs calcium and phosphorus to aid in the development of bones and teeth
Promotes normal cell growth and maturation
Prevents rickets
Maintains a healthy nervous and immune system
Treats low blood calcium with patients with kidney disease
Potential reduction in breast and colon cancer
Aging symptoms may be treated

The Following May Benefit from Taking Vitamin D:
Kids living in places with little sunshine
Those who need additional nutritional intake
People over 55 who receive little sunshine, such as those in nursing homes
Pregnant or breastfeeding women
Substance abusers
Those under prolonged stress
Those with partially removed intestinal tracts
Dark-skinned individuals
Babies who are breastfed
Vegan vegetarians
Cystic fibrosis patients

Where This Vitamin is Found:
Cod-liver oil
Egg substitutes
Halibut-liver oil
Herring
Mackerel
Salmon
Sardines
Sunlight
Tuna
Vitamin-D-fortified milk

How to Use:
Available as:
Liquid: the best form due to its high bioavailability and fast absorption. Always choose liquid as your first choice when supplementing your diet.
Tablets: available
Recommended Daily Intakes
Men: 200 IU
(over 50) 400 IU
(over 70) 600 IU
Women: 200 IU
(over 50) 400 IU
(over 70) 600 IU
Pregnancy: 200 IU
Lactation: 200 IU

Cautions:
Consult your doctor if you have:
Have planned pregnancy while taking vitamin D
Epilepsy
Heart or blood-vessel disease
Kidney, liver or pancreatic disease
Chronic diarrhea
Intestinal problems
Sarcoidosis

Over 55:
Higher potential for adverse reactions and side effects.

Pregnancy:
Always consult doctor during pregnancy. Abnormalities within the fetus may occur in too high of a dose. Remember to keep within the DRI.

Breastfeeding:
It is vital to normal growth and development of the child to get the correct intake of vitamin D. Always consult doctor during lactation. Remember to keep within the DRI.

Storage:
Heat and/or moisture may alter the vitamin. Refrigeration is recommended.

Symptoms of Deficiency:
Symptoms include bone pain and tenderness and muscle weakness. In children, rickets may occur, in which bones lose calcium and become soft and curved. Without proper intake, there is an increased risk of osteoporosis, arthritis, and cancer.

Overdose:
Signs of Overdose:
High blood pressure
Irregular heartbeat
Nausea
Weight loss
Seizures
Abdominal pain
Appetite loss
Mental-and physical-growth retardation
Premature hardening of arteries
Kidney damage

Side Effects:
Reaction or effect : What to do?
Loss of appetite : Discontinue. Refer to your doctor soon.
Constipation : Discontinue. Refer to your doctor soon.
Diarrhea : Discontinue. Consult doctor immediately.
Dry mouth : Discontinue. Refer to your doctor soon.
Headache : Discontinue. Consult your doctor immediately.
Increased thirst : Discontinue. Refer to your doctor soon.
Mental contusion : Discontinue. Consult your doctor immediately.
Nausea or vomiting : Discontinue. Consult your doctor immediately.
Unusual tiredness : Discontinue. Refer to your doctor soon.

Interactions:
Interacts with : Combined effect
Antacids with aluminum : Absorption of vitamin D reduced.
Antacids with magnesium : People with kidney failure should be aware of possibly too much magnesium
in the blood.
Anticonvulsants : Vitamin efficacy may be reduced.
Barbiturates : Vitamin efficacy may be reduced.
Calcitonin : Calcitonin effect reduced when treating hypercalcemia.
Calcium (high doses) : Risk of hypercalcemia increased.
Cholestyramine : Vitamin absorption reduced.
Colestipol : Vitamin absorption reduced.
Cortisone : Vitamin absorption reduced.
Digitalis preparations : Heartbeat irregularities increased.
Diuretics, thiazide : Hypercalcemia risk increased.
Hydration : Vitamin efficacy may be reduced.
Mineral oil : Absorption of vitamin D increased.
Phosphorus- containing medicines : Risk increased of too much phosphorus in blood.
Primidone : Vitamin efficacy may be reduced.
Vitamin-D derivatives : Increased potential for toxicity due to additive effects.
Alcohol : Depletes storage of vitamin D in liver.
 

Acidophilus (Lactobacillus)
Blue-Green Algae (Spirulina, Spirulina Maxima) Spirulina Platensis
Calcium (Calcium citrate) Calcium Gluconate)
Choline
Chondroitin Sulfate
Coenzyme Q (CoQ, Ubiquinoe, Coenzyme Q10)
Conjugated Linoleic Acid (CLA)
Creatine
Dehydroepiandrosterone (DHEA)
Desiccated Liver (Dessicated Liver)
Gamma-Linolenic Acid (GLA) Evening Primrose Oil)
Ginkgo Biloba (Ginkgoaceae)
Ginseng (Asian, American, Korean, Chinese, Panax, Quinquefolius)
Inositol (Myoinositol)
Iron (Ferrous Sulfate)

 
Jojoba (Goatnut, Simmondsia Chinensis)
L-Carnitine
Lecithin (Phosphatidylcholine)
Magnesium
Melatonin
Omega 3 Fatty Acids
Para-Aminobenzoic Acid (PABA)
Potassium (Potassium Chloride, Trikates)
Pregnenolone
Royal Jelly
Vitamin B-1 (Thiamine)
Vitamin B-2 (Riboflavin)
Vitamin B-3 (Niacin)
Vitamin B-5 (Pantothenic Acid)

 
Vitamin B-6 (Pyridoxine, pyridoxal phosphate)
Vitamin B-9 (Folic Acid) Folate, Pteroyiglutamic Acid) Folacin)
Vitamin B-12 (Cyanocobalamin)
Vitamin C (Ascorbic Acid)
Vitamin D (cholecalciferol, sunshine vitamin)
Vitamin E (alpha-tocopherol)
Vitamin H (Biotin)
Vitamin K (Phytonadione)
Vitamin P (Bioflavonoids, Phytochemicals)

Top Vitamin D Review Just Published

Findings from a review on vitamin D showed the various health benefits provided by vitamin D and the consequences of vitamin D deficiency. Without vitamin D, the small intestine would only be able to absorb 10 percent to 15 percent of our dietary calcium intake, which could lead to osteoporosis.

Other health consequences of vitamin D deficiency include:

Exposure to sunlight supplies us the majority of our vitamin D our bodies require. Darkly pigmented skinned people are the exception because they require 10 to 15 times exposure to the sun to get the same effect as lighter skinned people.

For those people who don’t get adequate amounts of sunlight, experts recommend a minimum of 1,000 IU vitamin D to maintain healthy levels in their blood. A high number of vitamin D deficiency cases have been found in infants who are solely breastfed from adults who have darker skin or lower exposure to the sun. Vitamin D has also often been misdiagnosed as fibromyalgia.

Many studies have shown how effective sunlight is with producing vitamin D in the skin. Since few foods contain vitamin D, sunlight provides us with most of the vitamin D we need.

Vitamin D deficiency has been becoming a growing epidemic across the world and is contributing to many chronic debilitating diseases.

American Journal of Clinical Nutrition March, 2004;79(3):362-371

Vitamin D Deficiency is Major Health Risk

Vitamin D deficiency has placed many Americans, particularly African Americans, in the higher risk bracket for developing bone problems and several other kinds of diseases.

Evidence of this increasing problem could be seen in the number of cases popping up of children afflicted with rickets, a vitamin-D-related bone disorder once thought to be a condition of the past. Also, doctors have been experiencing a number of adults who suffered with serious muscle pain and atrophy until they were treated for vitamin D deficiency.

Studies have also suggested that vitamin D deficiency might heavily impact the elderly by making them prone to developing bone-thinning diseases such as osteoporosis and other bone-related problems including fractures.

Some of the other health problems associated with vitamin D deficiency include certain types of cancer, high blood pressure, depression and immune system disorders. Because of these concerns, many scientists have requested official vitamin D recommendations.

Experts who advise more sun exposure as a way to get vitamin D have stirred up many emotions among skin cancer experts who expressed concerns over people ignoring the warnings on protecting their skin while spending time in the sun.

Vitamin D Facts

  • Skin has the natural ability to produce vitamin D when struck by ultraviolet rays in sunlight.

  • The amount of vitamin D a person needs depends on factors such as where they live, their skin pigment, age and other factors.

  • African Americans and other dark-skinned people and those living in northern latitudes make significantly less vitamin D than other groups.

  • Very few people get their vitamin D requirements through their diet.

  • Studies showed very low levels of vitamin D among children, the elderly and women.

  • One nationwide study of women revealed that almost half of the African American women of childbearing age might be vitamin D deficient.

Washington Post May 21, 2004

Should Vitamin D be Given to Cancer Patients?

Vitamin D has proven to aid in the treatment of many health conditions. However, researchers are driven to uncover if this vitamin is beneficial in treating cancer.

At a national conference researchers debated over whether or not plain vitamin D worked more effectively than a potentially profitable form of vitamin D, specifically designed to treat cancer.

Some questions researchers hoped to find answers to included:

  • Should patients take supplemental vitamin D in addition to the standard cancer treatment?

  • Should patients be treated for vitamin D deficiency?

However, in the midst of these questions, the discussion took a turn and boiled down to one main focal point: calcitriol.

Calcitriol, the most potent steroid hormone in the human body, is produced in large amounts in the tissues of vitamin D-filled individuals. However, in patients with cancer, vitamin D is in low supply. It is for this reason that some researchers proposed to develop an analogues form of this vitamin to fill up those patients' tanks.

For these reasons, most believe vitamin D should without a doubt be given to cancer patients, in addition to the standard cancer treatment. This theory here is that the vitamin D will significantly increase tissue levels of calcitriol, which in turn has outstanding anticancer properties.

A downfall to this theory is that intravenous calcitriol and its analogues cause hypocalcaemia, or high blood calcium. Plain vitamin D does not have this problem.

Reports have shown that plain vitamin D helps with the following types of cancer:

  • Colon

  • Prostate

  • Pancreatic

  • Breast, ovarian and cervical

The studies concluded that vitamin D analogues may help certain types of cancer, but it does not provide a cure, nor it will not treat vitamin D deficiency. Researchers agreed that the best route to fighting cancer is to have a sufficient intake of natural vitamin D to create more calcitriol.

In addition, plain vitamin D may also help prevent normal cells from turning cancerous. Vitamin D nutrition may also help common health-conditions linked to cancer such as hypertension, type 2 diabetes, heart disease, chronic pain and osteoporosis.

Medical News Today October 11, 2004

The Secret Benefits of Vitamin D

Vitamin D plays a much larger role in regulating health, than simply promising strong bones. Researchers from around the globe have discovered that getting the recommended daily vitamin D intake could help reduce plaguing health risks such as MS and diabetes.

Ordinarily, a vitamin is an essential element the body cannot create on its own; however, it is possible for people to create all the vitamin D they need from a cholesterol-like precursor.

For adults, the recommended amount of international units (IU) of vitamin D per day should be between 200 to 600 IU, though most people don’t even come close to that. During the summer months that goal is easily reached, as the human body can generate up to 12,000 IU of vitamin D from only half an hour of sun exposure. However, during winter months, the daily intake people derive from food and sun exposure falls way below the recommended amount.

Further, people who live farther from the equator find it extremely difficult to get enough sun to maintain sufficient blood concentrations of the vitamin.

By running tests, researchers attempted to discover the myriad of benefits vitamin D has to offer.

They found that the vitamin helps regulate cell growth, immunity and energy metabolism. It also could possibly serve as a model for drugs that might tame a range of stubborn, hard to treat diseases.

Benefits of Vitamin D Include:

  • Protection against multiple sclerosis (MS)

  • Prevention of diabetes

  • Signals colon, breast and prostate cells to stop growing and eventually succumb to programmed cell death

One common concern linked to not getting enough vitamin D is leg weakness. According to studies, people who had higher readings of vitamin D also had greater thigh strength. Researchers conducted deficiency studies and found that with a daily vitamin D intake of at least 400 IU, a woman’s risk of being injured in a fall was decreased by 20 percent.

Another group of researchers who linked vitamin D to immune benefits found that subjects given the lowest amount of vitamin D intake were 25 percent more likely to experience tooth-gum detachment than subjects given the highest intake of the vitamin.

Science News October 9, 2004;166(15)

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