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Zollinger-Ellison syndrome
Zollinger-Ellison Syndrome is a rare condition that causes severe stomach ulcers. Zollinger-Ellison syndrome is a condition in which one or more tumors form in the pancreas or in the upper part of the small intestine (duodenum). These tumors, called gastrinomas, secrete large amounts of the hormone gastrin, which causes excessive production of acid in your stomach, leading to peptic ulcers. The ulcers that occur as part of Zollinger-Ellison syndrome are typically more resistant to treatment than other ulcers, may recur after initial treatment, are often numerous and may occur in unusual areas of your stomach or intestine. Only a tiny percentage of all people with peptic ulcers have Zollinger-Ellison syndrome. It may occur at any age, but it's more likely to occur in people between the ages of 30 and 60. The approach to treatment is dual - medications to reduce acid and heal the ulcers, and, if possible, surgery to remove the tumors.
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