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Sjogren's syndrome
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Sjogren's syndrome

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Complications

Many of the complications of Sjogren's syndrome are more annoying than serious. But serious problems can develop, especially if you have a rheumatic disease along with Sjogren's syndrome. Common complications of Sjogren's syndrome include:

  • Difficulty swallowing. Lack of saliva may make it more difficult for you to chew and swallow.

  • Dental cavities. Because saliva helps protect the teeth from bacteria, you are more prone to developing cavities if your mouth is dry.

  • Vision problems. Dry eyes can lead to light sensitivity, blurred vision and corneal ulcers.

Less common complications include:

  • Inflammation of organs such as your lungs, kidneys or liver. Inflammation may cause pneumoni, bronchitis or other problems in your lungs; may lead to problems with kidney function; and may cause hepatitis or cirrhosis in your liver.

  • Heart problems for babies born to mothers with Sjogren's syndrome. If you're a woman with Sjogren's syndrome and you plan to become pregnant, talk with your doctor about being tested for certain autoantibodies that may be present in your blood. These antibodies, anti-Ro (anti-SS-A) and anti-La (anti-SS-B), have been associated with a neonatal lupus syndrome, which can cause a rash on your baby that will clear up within a few months. In rare cases this antibody is associated with heart problems in newborns.

  • Cancer of the lymph nodes (lymphoma). A small percentage of people with Sjogren's syndrome develop lymphoma. Symptoms include swelling of the salivary glands, fatigue, weight loss and night sweats.

  • Peripheral nervous system disorders. Peripheral neuropathies are common in people with Sjogren's syndrome. Your legs may be especially affected and you may experience symptoms of numbness, tingling and burning. Your cranial nerves — such as those relating to your eyes (optic nerve) or face (trigeminal nerve) — can be affected and may cause visual problems or facial pain.

Sjogren's syndrome > 1 > 2 > 3 > 4

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