The Dangers of Vaccinations
The Controversy of the Latent Period Following Immunizations In 1986 the U.S.
Congress passed the National Childhood Vaccine Injury Act, which set
up a system whereby the families of vaccine-injured children could
be compensated for such injuries. Based on personal experience and
observation, there has been much criticism of this system and
question whether not it is serving its intended purpose.
Tetanus Toxoid Vaccination
Tetanus as a clinical entity is linked to a bacteria, Clostridium tetani.
Obviously, the germ is not as malicious as one may think because it
lives as a harmless commensally in the animal and human intestinal tract
(1). It is not the very presence of the bacteria which causes the
trouble, but the toxins that are produced by the bacteria under
anaerobic conditions, that is, where the bacteria operates in an
environment free of oxygen. These toxins can be spread through the blood
vessels and finally affect the nervous system causing tetanic muscle
contraction and pain. The condition is extremely painful and potentially
tetanus vaccine is no more effective than any of the others. It also
is counterproductive. It will INCREASE, NOT decrease the risk of
tetanus, and many people actually get
tetanus from the vaccine.
You have every right to closely question me on the
since that was the last vaccine I abandoned. (4/6/2003)
Chickenpox Vaccine Works LESS Than Half The Time...
New study findings indicate that, at least among one group of children,
the varicella vaccine is much less effective than previously reported.
VACCINATIONS--The Hour of the Time...
Most of you out there have probably received some form of vaccination at
one point or another in your life, or you may have children who are in
the process of receiving vaccinations. Well, I have some very bad news
for you folks... (1/8/2003)
The Controversy of the Latent Period Following Immunizations
by Harold E
In 1986 the U.S. Congress passed the National Childhood Vaccine Injury
Act, which set up a system whereby the families of vaccine-injured
children could be compensated for such injuries. Based on personal
experience and observation, there has been much criticism of this system
and question whether not it is serving its intended purpose.
(1) One of the major areas of controversy surrounding the act involves
its limitations in the latent periods, whereby certain defined reactions
following vaccines must be identified within a certain time period to
qualify for compensation by the childhood vaccine injury act. For the
complication of encephalitis, the time limitation for the DTP or DTaP
vaccine is 3 days; for the measles-mumps-rubella (MMR) vaccine it is 5
to 15 days.
The limitations in latent periods following vaccines have been generally
accepted by our medical-legal system as guidelines in other areas as
well. Prominent among these is the "shaken baby syndrome" (SBS) in which
a parent or caretaker is accused of injuring or murdering an infant by
violent shaking and causing a triad of findings now commonly accepted as
diagnostic of SBS: retinal hemorrhages, subdural hematomas, and diffuse
axonal injury. (2-5)
However, it has been observed that many cases attributed to the SBS have
occurred in a time-related fashion following routine childhood vaccines,
especially in compromised children that had been born from medically
complicated pregnancies. (6) Consequently there are valid reasons for
questioning whether or not some or many cases that have been accused of
SBS were not the result of mistaken diagnoses, the true causes of death
or injury of the child having been vaccines.
Since questions surrounding the latent period play a prominent role in
many of these cases, it is timely and appropriate to review the
background of this issue.
Current Guidelines in the Latent Period Artifactual?
The DTP (diphtheria-tetanus-pertussis) Vaccine:
If we think in terms of a vaccine-induced encephalitis, most of the
earlier literature deals with the pertussis vaccine. Flexner (1930)
noted a strong tendency for the nervous system manifestations to declare
themselves between the 10th and 13th days. (7)
In a review of 108 cases recorded before 1929 by Gorter (1933) , the
onset of encephalitis was "strikingly constant," usually observed
between the 10th and 12th days following vaccination, commonly with a
febrile period on the 7th and 8th days, followed by recovery until onset
of the encephalitis. (8)
In 1929 an editorial in the Journal of the American Medical Association
reported on an increase in severe neurological complications following
infections and inoculations occurring on about the 11th day after
vaccines. (9) Over 50 years later Munoz, (1984) in a mice study of
experimental encephalomyelitis elicited by injection of pertussigen,
found the same latent period of 11 to 13 days. (10)
In contrast, some of the literature since the 1970s has reported an
entirely different pattern, with the onset of encephalopathy largely
falling within a 3-day period following vaccines. (11-13) We can only
speculate as to the reasons for this changing pattern.
Perhaps it can be attributed to the fact that, in those early years,
children were given very limited numbers of vaccines in comparison with
more recent years during which they have routinely received the
hepatitis B, H influenza, and polio vaccines in addition to the DTP, all
given at the same time.
The hepatitis B vaccine has been implicated in neurological disorders,
autoimmune disorders, various forms of vasculitis and cutaneous
reactions, as well as hemorrhagic complications. (See below, page 6)
Both the pertussis and H influenza vaccines have been shown to have
unusually high hyper-sensitizing properties. (14) In many vaccines thimerosal, which contains ethyl mercury, has been added as a
preservative. (In some vaccines its use dates back to the 1930s.)
Thimerosal has also been found to have sensitizing properties. (15)
Consequently there are valid reasons for believing that the pertussis
and H influenza vaccines, some of which contain mercury, may be acting
in a three-way synergy in causing hypersensitivity reactions.
In the text, Vaccinations and Behavioral Disorders, by Greg Wilson, the
author made the following comment in regards to the latent period:
"Today the latent period is rarely mentioned in connection with
neurological complications of immunization ... Contemporary studies on
the pertussis vaccine select an arbitrary time limit in which reactions
have to occur to be considered as vaccine related. This time limit is
usually 3 to 7 days.
"Perhaps the only study which explores the dynamics of post DPT
reactions is an independent Australian study by Karlsson and Scheibner
which, with a monitor which followed breathing volumes, found particular
times of stress-induced breathing following DPT injections." (16) "Of
special importance (for stress) are days 2,5,6, and 8,11,13-16 and
By way of explanation, the above study involved the use of a Cotwatch
breathing monitor controlled by a micro-processor and designed to
provoke alarms with breathing delays (apnea of hypopnea with 5% or less
of normal breathing patterns) following DTP immunizations. It was found
in the study that these periods of stressed breathing occurred in
clusters of 15 minutes at a time on the post-vaccine days listed above,
varying greatly from child to child.
From our point of view, the important feature of the study is not so
much the specific post-vaccine days on which the stressed breathing
occurred but the fact that the clusters continued for 21 days following
the vaccines, (18) which would tend to discredit the current
medical-legal limitation for DPT reactions to 3 days.
Dr. Scheibner's findings do have some support in a study which showed a
fairly high incidence of cardio-respiratory complications in premature
infants following vaccinations. (19) Unfortunately, this study was of
Another study throwing light on the latent period is one coming from
Japan, from which it was found that increased histamine sensitivity in
mice, brought about by the pertussis vaccine, showed two peaks, one on
the 4th day following vaccination, and a second on the 12th day. (20) In
the same vein, in a letter to the British Medical Journal, Rosemary Fox,
secretary of Parents of Vaccine Damaged Children, made the following
"Two years ago we started to collect details from parents of serious
reactions suffered by their children to immunizations of all kinds. In
65% of the cases referred to us, reactions followed the triple vaccine
(diphtheria-pertussis-tetanus). The children in this group total 182 to
date; all are severely brain damaged, some are also paralyzed, and 5
have died. Approximately 60% of reactions ... occurred within 24 hours
of vaccination, 80% within 3 days, and all within 12 days." (21)
It is important to point out in the above-survey that 20% of reactions
occurred beyond the current 3 day medical-legal limitation for the DPT
Another important study throwing light on the latent period involves an
unpublished series of 25 cases with accusations or convictions of
parents or caretakers for the shaken baby syndrome, a series collected
by attorney Toni Blake of San Diego, California (personal communication,
2000) which have the following features: 1) All occurred in fragile
infants born from complicated pregnancies.
Problems included prematurity, low birth weights, drug/alcohol problems,
diabetic mothers, or other maternal complications. 2) All infants were 6
months age or less. 3) Onset of signs and symptoms occurred at about
2,4, or 6 months of age, WITHIN 12 DAYS OF VACCINES, 4) All infants had
subdural hematomas. 5) Some had multiple fractures.
In addition to the work of Dr Viera Scheibner and attorney Toni Blake,
another enlightening area of study for the latent period is the federal
Vaccine Adverse Events Reporting System (VAERS). In her book, What Your
Doctor May Not Tell You About Children's Vaccinations, (22) Dr.
Stephanie Cave makes the following observations about VAERS:
"It is common knowledge that less than 10% of all adverse events
following vaccinations are reported to VAERS, which means that instead
of the 12,000 to 14,000 reports of hospitalizations, injuries, and
deaths made every year, there may be as many as 120,000 to 140,000."
Even a cursory examination of the VAERS database for DTP/DTaP vaccines
will reveal that the latent periods for many vaccine reactions extend
into the 7 to 13 day periods, some extending beyond 14 days. (23)
No review of the latent period would be complete without pointing out an
almost insuperable difficulty in getting dependable data on these
reactions due to the extreme reluctance of doctors to report on vaccine
reactions, a pattern which has existed since the earliest days of
childhood vaccines. There are a number of reasons for this.
From their earliest years of training, medical doctors have been taught
to look upon vaccines as one of the greatest achievements in medical
science, and any question about the vaccines is often looked upon as
disloyalty to the profession. In addressing this issue in the classic
text, Shot in the Dark, by Coulter and Fisher, the authors quoted an
attorney specializing in vaccine-damaged children.
In commenting on the deficiency in doctors' reporting of vaccine
reactions, the attorney commented, "As is the case with many pertussis-vaccine-injured
children, none of the treating physicians would commit themselves to a
final etiological diagnosis. It is strange that parents of pertussis-vaccine-damaged
children often can only get an etiological diagnosis by hiring an
attorney and seeing one of the few recognized experts in the US on post-pertussis
vaccine encephalopathy." (25)
As a result of this physician-reluctance to report vaccine reactions,
large numbers of reactions may be taking place beyond the currently
established time limits of the latent period, unrecognized as to their
(B) The Hemophilus influenza (HiB) vaccine:
In one of the largest, if not the largest randomized epidemiological
trial ever conducted, the effect of the Hemophilus vaccine on the
development of insulin dependent diabetes mellitus (IDDM) was studied in
Finland. (26) All children born in Finland between October 1st, 1985 and
August 31st, 1987, approximately 116,000, were randomized to receive 4
doses of the HiB vaccine (PPR-D, Connaught) starting at 3 months of life
or one dose starting at 24 months of life.
An intent to treat method was used to calculate the incidence of IDDM in
both treatment groups until age 10. The incidence of IDDM was also
calculated in a control group of 128,500 children which did not receive
the HiB vaccine. (27) The results demonstrated a rise in IDDM which was
specific for the vaccinated cohort. (28)
However, the important point for our purposes was that there was a
consistent delay of 3.5 years between vaccination and onset of IDDM. (It
should be pointed out that IDDM is considered an autoimmune disease.)
At a presentation this past spring in Nashville, Tennessee sponsored by
the American College for the Advancement of Medicine, (29) Dr. John
Classen reviewed 32 publications in the medical literature showing a
similar increases in diabetes mellitus in a number of countries with the
MMR and hepatitis B as well as the HiB vaccine, again with latent
periods up to three years or more, according to graphs that were
provided. (Copies of references will be provided on request).
Rather than being specific to any one vaccine, Dr. Classen offered his
opinion that the general immune stimulation from the vaccines was the
cause of a rise in autoimmunity. As an interesting sidelight, Dr.
Classen mentioned that personnel in the US navy are more heavily
immunized than their European counterparts, and that the US navy
personnel have five times more diabetes than their European
The MMR (measles-mumps-rubella) vaccine:
Whereas DTP and Hib vaccine-related encephalopathy may be the result of
interactions between endotoxin and mercury, (the latter in the form of
the additive, thimerosal), the primary mechanism of viral vaccines in
causing encephalopathy may be related to the propensity of viruses (and
viral vaccines) in bringing about autoimmune reactions. (30)
In order to provide an overview of the latent period, there are two
basic classes of immune systems, the humoral or antibody producing
system, which tends to produce immediate-type reactions, and cellular
immunity, in which reactions are delayed. Either class is capable of
producing autoimmunity. (31) Obviously, the usual 15 day limitation for
the MMR vaccine excludes a recognition of the delayed-type autoimmune
reactions and, by inference, even denies their existence.
In an article by Cohen and Shoenfeld dealing with questions of
vaccine-induced autoimmunity, the authors pointed out that it is a
subject about which relatively little is known, due to the paucity of
clinical and laboratory studies. (32) In point of fact a more recent
review on this subject cites a temporal relationship of 2 to 3 months
between vaccines and autoimmune reactions. (33)
Recently the subject of the latent periods for the MMR vaccine came
sharply into focus in an article published in Adverse Drug Reaction &
Toxicology Review, (34) in which researchers Andrew Wakefield and Scott
Montgomery, who have been investigating a possible causal relationship
between the MMR vaccine and the autism-enterocolitis syndrome, carefully
reviewed deficiencies in the early pre-licensing trials of the MMR
In the article they pointed out that follow up periods following the
vaccine were a maximum of 28 days and in some studies even shorter
periods. They stressed that such short periods of observations following
the vaccine were totally inadequate to detect delayed reactions,
including pervasive developmental delay (autism), immune deficiencies,
and inflammatory bowel disease, which are known from earlier published
reports to occur following both the natural measles infection and the
The most interesting feature of the Wakefield/Montgomery article was
that it was reviewed by four leading British authorities, all of whom
had previously held positions in the regulation and licensing of
medicines in the United Kingdom. (35) Taken as a whole, the reviewers
were supportive of the article, three highly so.
Peter Fletcher, formerly a senior professional medical officer for the
Department of Health wrote, "being extremely generous, evidence of
safety (of the MMR vaccine) was very thin." Noting that single vaccines
for measles, mumps, and rubella already existed, he argued, "caution
should have ruled the day ... granting of a product license was
Professor Duncan Vere, former member of the Committee on the Safety of
Medicines, agreed that the periods for tests were too short. "In almost
every case," he wrote, "observation periods were too short to include
the onset of delayed neurological or other adverse events."
The Hepatitis B vaccine:
Other than the references provided by John Classen, M.D. on the findings
of increased diabetes from the hepatitis B vaccine with a latent period
of 3 years, I am not aware of additional information bearing on the
latent periods between hepatitis B vaccine and other forms of reactions,
which reflects the sheer lack of data on the subject.
However, many reactions to hepatitis B vaccine may be taking place
unrecognized, for two reasons: Reason one, I have in my possession a
list of 109 references of published articles reporting on complications
from the hepatitis B vaccine including autoimmune disorders,
neurological disorders, vasculitis and cutaneous reactions. This list
will be provided on request.
For reason two, in 1994 a special committee of the national Academy of
Sciences (Institute of Medicine) published a comprehensive review of the
safety of the hepatitis B vaccine. When the committee, which carries the
responsibility for determining the safety of vaccines by Congressional
mandate, investigated five possible and plausible adverse effects, they
were unable to come to conclusion for four of them because they found
that relevant safety research had not been done.
Furthermore, they found that serious "gaps and limitations" exist in
both the knowledge and infrastructure needed to study vaccine adverse
events. Among the 76 types of vaccine adverse events reviewed by the
IOM, the basic scientific evidence was inadequate to assess definitive
vaccine causality for 50 (66%). The IOM also noted that "if research ...
(is) not improved, future reviews of vaccine safety will be similarly
For this reason, the published reports of hepatitis B vaccine reactions
may only be a small portion of those actually taking place, with large
numbers of delayed reactions taking place unrecognized.
Based on published evidence that many vaccine reactions take place
beyond current medical-legal time limits that have been established for
vaccines, and on overwhelming evidence that large numbers of delayed
vaccine reactions may be taking place unrecognized, there are grounds
for believing that these time limitations may be unrealistic and
(1) Buttram HE,
The National Vaccine Childhood Injury Act - a Critique, Townsend Letter
for Doctors & Patients, October, 1998:66-68.
(2) David TJ,
Shaken baby (shaken impact) syndrome; non-accidental head injury in
infancy, Royal Soc Med, Nov., 1999; 99:556-561.
(3) Weston IT, The
pathology of child abuse, in: Heifer RE, Kempe CH, editors, The Battered
Child, University of Chicago Press, 1968:77-100.
(4) Caffey J, On
the theory and practice of shaking infants; its potential residual
effects of permanent brain damage and mental retardation, Am J Dis
Child, 1972; 124:161-169.
(5) Guthkelch AN,
Infantile subdural hematoma and its relationship to whiplash injury,
Brit Med J, 1971; 11:430-431.
(6) Buttram HE,
Shaken baby syndrome or vaccine-induced encephalitis?, Medical Sentinel,
Fall, 2001; 6(3):83-89.
(7) Flexner S,
Postvaccinal encephalitis and allied conditions, JAMA, 1930;
(8) Gorter E,
Postvaccinal encephalitis, JAMA, 1933; 101(24):1871-1874.
(editorial), Postinfectious encephalitis, a problem of increasing
importance, May, 1929; 92(18):1523-1524.
(10) Munoz JJ et
al, Elicitation of experimental encephalomyelitis in mice with the aid
of pertussigen, Cellular Immunology, 1984; 83(1):92-100.
(11) Menkes JH &
Kinsbourne M, Workshop on neurologic complications of pertussis and
pertussis vaccination, Neuropediatrics, 1990; 21:171-176.
(12) Menkes JH,
Neurologic complications of pertussis vaccination, Ann Neurology, 1990;
(13) Cody CL et
al, Nature and rates of adverse reactions associated with DTP and DT
immunization in infants and children, Pediatrics, Nov., 1981;
(14) Terpstra OK
et al, Comparison of vaccination of mice and rats with Hemophilus influenza and Bordetella pertussis as models, Clin Exp Pharmacol Physiol,
March-April, 1979; 6(2):139-149.
(15) Patrizi A et
al, Sensitization to thimerosal in atopic children, Contact Dermatitis,
Feb., 1999; 40(2):94-97.
and Behavioral Disorders, a Review of the Controversy, Greg Wilson,
Tuntable Creek Publishing, PO Box 1448, Lismore NSW 2480, Australia,
2000, pages 48-49.
(17) Karlsson L &
Scheibner V, Association between non-specific stress syndrome, DPT
injections and cot death, paper presented to the 2nd immunization
conference, Canberra, May 27-29, 1991.
100 Years of Orthodox Research Shows that Vaccines Represent a Medical
Assault on the Immune System, Viera Scheibner, Ph.D., Australian Print
Group, Maryborough, Victoria, Australia, 1993, pages 230-235.
(19) Pourcyrous M
et al, Interleukin-6, C-reactive protein, and abnormal cardiorespiratory
responses to immunization in premature infants, Pediatrics, March, 1998;
(20) Horiuchi S et
al, Two different histamine-sensitizing activities of pertussis vaccine
observed in mice on the 4th and 12th days of sensitization, Japan J Med
Sci Biol, 1993; 46:17-27.
(21) Fox R,
letter, British Med J, Feb. 21, 1976.
(22) What Your
Doctor May Not Tell You About Children's Vaccinations, Stephanie Cave,
M.D., F.A.A.F.P., Warner Books, An AOL Time Warner Company, 2001, page
Databases: www.vaers.org, www.fda.gov/cber, orwww.fedbuzz.com/vaccine/vacmain.htm
(24) Reisinger RC, A final mechanism of cardiac and respiratory failure,
SIDS, 1974, Proc of Camps Intern Symp on SID in Infancy; also
Congressional Record S. 1745, September 20, 1973.
(25) A Shot in the
Dark, Harris L Coulter & Barbara Loe Fisher, Avery Publishing Group,
Inc., Garden City Park, New York, 1991, Page 47.
(26) Classen JB,
Classen DC, Association between type I diabetes and Hib vaccine, causal
relation likely, British Med J, 1999; 319:1133.
(27) Tuomilehto J,
Virtala E, Karvonen M et al, Increase in incidence of
insulin-dependent diabetes mellitus among children in Finland, Intern J
Epidemiology, 1995; 24:984-992.
(28) Tuomilehto J,
Karonen M, Pitkaniemi J et al, Record high incidence of type 1 (insulin
dependent) diabetes mellitus in Finnish children, Diabetologia, 1999;
College for the Advancement of Medicine, 23121 Verdugo Dr., Ste. 204,
Laguna Hills, CA 92653, phone 949-583-7666, fax 949-455-0679.
(30) Singh V & V
Yang, Serological association of measles virus and human herpes virus-6
with brain autoantibodies in autism, Clin Immunol and Immunopath, 1998;
Charles A Janeway et al, fourth Edition, Current Biology Publications,
New York, 1999, page 495.
(32) Cohen DC &
Shoenfeld Y, Vaccine-induced autoimmunity, J Autoimmunity, 1996;
(33) Shoenfeld Y &
A Aron-Maor, Vaccination and autoimmunity-'vaccinosis:' a dangerous
laison?, J Autoimmunity, Feb., 2000; 14(1):1-10.
(34) Wakefield AJ
& S Montgomery, Measles, mumps, rubella vaccine: through a glass darkly,
Adv Drug React Toxicol Rev, Jan., 2001; 19(3):1-19.
(35) Hurley DR, DW
Vere, AP Fletcher, Referee 1, 2, 3, & 4, Adverse Drug React Toxicol Rev,
2001; 19(4): 1-2.
(36) Stratton KR,
CJ Howe and RB Johnston, Jr., Editors, Adverse Events Associated with
Childhood Vaccines; Evidence Bearing on Causality, Institute of
Medicine, National Academy Press, Washington D.C., 1994, pp 211-236.