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Rabies
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Rabies

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INFECTIOUS DISEASE

Viral Illnesses

Rabies is a serious viral disease that affects the central nervous system of mammals. The disease typically spreads by way of the saliva of infected animals - often, but not always, through a bite.

Once you're infected, the virus spreads from peripheral nerves to your spinal cord and brain. From initial flu-like signs and symptoms, the illness can progress to convulsions, paralysis or breathing failure. Death can occur if you don't seek treatment immediately after exposure.

Treatment

If your doctor determines that you likely were exposed to rabies, treatment begins at once. The sooner you begin treatment, the greater your chance of recovery.

Treatment for rabies after an animal bite, treatment — called post-exposure prophylaxis — consists of one dose of rabies immunoglobulin and five doses of rabies vaccine over a 28-day period. Rabies immunoglobulin and the first dose of rabies vaccine are administered as soon as possible after you've been exposed and have reported the exposure to your doctor. You're given the immunoglobulin by injection around the site of the bite, and you receive injections of the vaccine into your upper arm muscle.

Immunoglobulins are disease-fighting proteins that provide you with temporary antibodies. The rabies vaccine helps your body start producing its own antibodies. Antibody production takes time, but the antibodies produced by your body provide longer-lasting protection than do the ones contained in rabies immunoglobulin.

The three types of rabies vaccines are all made from killed rabies virus:

  • Human diploid cell rabies vaccine (HDCV), the most commonly used vaccine

  • Rabies vaccine adsorbed (RVA)

  • Purified chick embryo cell vaccine (PCEC)

You might have a mild physical reaction to the vaccines. Watch for reactions such as swelling or redness where the injection occurred. Headache, fever, nausea, muscle aches and dizziness are other possible side effects. Contact your doctor if side effects cause you discomfort.

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Last Modified : 03/15/08 02:01 AM