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Hypopituitarism

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DIABETES AND ENDOCRINE SYSTEM

Endocrine System

Hypopituitarism is a disorder in which your pituitary gland fails to produce one or more of its hormones, or doesn't produce enough of them. A short supply of one or more of these pituitary hormones can affect any number of your body's routine functions.

While physicians rarely diagnose hypopituitarism, they should be aware of the signs and symptoms that characterize this disorder. The pituitary gland plays a major role in the endocrine system, linking the endocrine system and the CNS.

The pituitary is a small bean-shaped gland located at the base of your brain, somewhat behind your nose and between your ears. It's part of your endocrine system, which consists of glands that produce hormones that regulate processes throughout your body. Besides the pituitary gland, the endocrine system includes the thyroid gland, parathyroid glands, adrenal glands, pancreas, ovaries (in females) and testicles (in men).

Causes

Hypopituitarism is frequently triggered by a tumor of the pituitary gland. Although pituitary tumors are usually noncancerous (benign), they can increase in size. Because they grow in such limited space, they can compress and damage pituitary tissue, interfering with hormone production. A tumor can also compress the optic nerves, slowly causing a loss of vision.

The cause of hypopituitarism can also be other diseases and events that damage the pituitary, such as:

  • Head injuries

  • Brain surgery

  • Radiation treatment

  • Stroke

  • Infections of the brain, such as meningitis

  • Tuberculosis

  • An injury to the mother during childbirth that is complicated by excessive blood loss and low blood pressure

  • Autoimmune inflammation, in which your immune system attacks healthy tissue

  • Some uncommon diseases, such as sarcoidosis, which is an inflammatory disease occurring in various organs, and histiocytosis X, in which abnormal cells cause scarring in numerous parts of the body, such as the lungs and bones

Diseases of the hypothalamus, a portion of the brain located just above the pituitary, also can cause hypopituitarism. The hypothalamus produces hormones of its own that directly affect the activity of the pituitary.

In some cases, the cause is unknown.

Hypopituitarism > 1 > 2 > 3 > 4

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This information is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition.
In no event will The DrEddyClinic.com be liable for any decision made or action taken in reliance upon the information provided through this web site.

 


 



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Last Modified : 03/15/08 01:06 AM