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Guillain-Barre
syndrome
(GBS)
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U | Guillain-Barre syndrome (GBS) is an
inflammatory disorder in which your body's immune system attacks the
nerves outside the brain and spinal cord (peripheral nerves) and,
rarely, parts of the brain itself. Severe weakness and numbness in your
legs and arms characterize GBS. Loss of feeling and movement (paralysis)
may occur in your legs, arms, upper body and face. It can strike any race at any age, but
its incidence increases with age. GBS may occur within days or weeks
after a viral infection such as influenza (flu) or
diarrhea. It may be triggered by pregnancy or a medical procedure, such
as a vaccination or minor surgery, or have no evident reason for
developing. Because the cause of GBS is unknown, there's no way to
prevent the disease from occurring. In its most severe form, GBS is a
medical emergency and may require hospitalization. Severe GBS may result
in total paralysis, potentially dangerous fluctuations in heart rate and
blood pressure and inability to breathe without respiratory assistance.
The muscles you use for eye movement, speaking, chewing and swallowing
also may become weak or paralyzed. People with severe GBS often need
long-term rehabilitation to regain normal independence. GBS is
life-threatening and fatal in up to 15 percent of cases, and risk of
death is likely to be higher in older adults with other medical
problems. Most people recover from even the most severe cases of GBS, although some people continue to have some weakness. However, long-term impairment is possible, with approximately 20 percent of those with GBS having permanent disability, and about two-thirds having ongoing fatigue. Signs and symptoms The signs and symptoms of GBS usually appear rapidly over the course of a single day. These may include:
GBS progresses quickly, with most people experiencing the worst weakness in the legs, arms, chest and other areas within three weeks of the start of the disease. In some cases, the signs and symptoms of GBS may progress very rapidly with complete paralysis of legs, arms and breathing muscles over the course of a few hours. If GBS is mild, the signs and symptoms may not extend beyond a feeling of general weakness. GBS may improve on its own within a few weeks, and some people initially may think the signs and symptoms are due simply to a common virus. The signs and symptoms of GBS may last days, weeks or months before muscle sensation begins to return. Regaining your pre-illness strength and functioning is slow, sometimes requiring months or years. However, most people with GBS return to normal within months. Guillain-Barre syndrome (GBS) > 1 > 2 > 3 > 4
Related Site: Treatments
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