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Glomerulonephritis
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Glomerulonephritis

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Acute glomerulonephritis refers to a specific set of renal diseases in which an immunologic mechanism triggers inflammation and proliferation of glomerular tissue. Hippocrates originally described the manifestation of back pain and hematuria, which lead to oliguria or anuria. With the development of the microscope, Langhans was able to describe the corresponding glomerular changes. Most original research focuses on the poststreptococcal patient.

Complications 

Complications of glomerulonephritis may include:

  • Acute kidney failure. Loss of function in the filtering part of the nephron may cause waste products to accumulate rapidly. This condition may require emergency dialysis, an artificial means of removing extra fluids and waste from your blood, typically by an artificial kidney machine (dialyzer). You'll also require restriction of your water and food intake.

  • Chronic kidney failure. In this extremely serious complication, the kidneys gradually lose function. Kidney function at less than 10 percent of normal capacity indicates end-stage kidney disease, which requires dialysis or a kidney transplant to sustain life.

  • High blood pressure. Damage to your kidneys and the resultant buildup of waste in the bloodstream can raise your blood pressure.

  • Nephrotic syndrome. This is a group of signs and symptoms that may accompany glomerulonephritis and other conditions that affect the filtering ability of the glomeruli. High protein levels in the urine resulting in low protein levels in the blood, high cholesterol, and swelling of the eyelids, feet and abdomen characterize the syndrome.

Glomerulonephritis > 1 > 2 > 3 > 4

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Last Modified : 03/15/08 12:53 AM