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Cushing Syndrome |
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Cushing's syndrome
From MayoClinic.com In Cushing's syndrome, the level of corticosteroids is excessive, usually from overproduction by the adrenal glands. The syndrome is named after Harvey Cushing, an American surgeon who first identified the condition in a woman in 1912. Cushing's syndrome can occur when your adrenal glands, located above your kidneys, make too much cortisol. It may also develop if you're taking high doses of cortisol-like medications (corticosteroids) for a prolonged period. These corticosteroids are commonly used to treat a variety of acute and chronic illnesses. Too much cortisol can produce some of the hallmark signs and symptoms of Cushing's syndrome — a fatty hump between your shoulders, a rounded face, and pink or purple stretch marks (striations) on your skin. It can also result in high blood pressure, bone loss and, on occasion, diabetes. Treatments for Cushing's are designed to return your body's cortisol production to normal. By normalizing, or even markedly lowering cortisol levels, you'll experience noticeable improvements in your symptoms. Left untreated, however, Cushing's syndrome can eventually lead to death. Cushing's syndrome associated with the use of corticosteroid medication is fairly common. By contrast, it's rare for the cause to be excess cortisol production by the body. Most of the latter cases occur in adults between the ages of 20 and 50 years old. Signs and symptoms The most common signs and symptoms of Cushing's syndrome are:
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