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Colorectal cancer - Colorectal Cancer, Colon Cancer, Rectal Cancer
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Colorectal cancer

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From MayoClinic.com

Risk factors

Colorectal cancer can occur at any age, and no one is too young to develop colorectal cancer. However, about 90 percent of people with the disease are older than 50. Factors other than age that place you at a higher risk include:

  • Inflammatory intestinal conditions. Long-standing inflammatory diseases of the colon, such as ulcerative colitis and Crohn's disease, can increase your risk.

  • Family history. You're more likely to develop colorectal cancer if you have a parent, sibling or child with the disease. If many family members have colon or rectal cancer, your risk is even greater. In some cases, this connection isn't hereditary or genetic. Instead, cancers within the same family may result from shared exposure to an environmental carcinogen or from diet or lifestyle factors. Familial adenomatous polyposis (FAP) is a rare hereditary disorder that causes you to develop hundreds of polyps in the lining of your colon and rectum, beginning in your teenage years. If these go untreated, you'll likely develop colon cancer by age 40. In most cases, genetic testing can help determine if you're at risk of FAP. FAP also causes polyps to develop not only throughout your colon but also, in most cases, eventually in your upper intestine or duodenum. You may also develop noncancerous tumors in other parts of your body, including your skin (sebaceous cysts and lipomas), bone (osteomas) and abdomen (desmoid tumors). Hereditary nonpolyposis colorectal cancer (HNPCC) is another hereditary disorder that can put you at high risk of developing colon or rectal cancer. Unlike FAP, however, you may have relatively few polyps. If you're Jewish and of Eastern European descent, you may have an inherited tendency to develop colorectal cancer. This is particularly true of Ashkenazi Jews.

  • Diet. Colorectal cancer may be associated with a diet low in fiber and high in fat and calories. Research is still occurring in this area. However, high-fiber, low-fat diets have additional health benefits apart from a potential connection to colorectal cancer prevention.

  • A sedentary lifestyle. If you're inactive, you're more likely to develop colon cancer, although not rectal cancer. This may be because when you're inactive, waste stays in your colon longer. Getting regular physical activity may reduce your risk of colon cancer.

 Colorectal cancer > 1 > 2 > 3 > 4

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