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Bipolar (Manic-Depressive) disorder
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Bipolar (Manic-Depressive) disorder

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MENTAL HEALTH

Mental Disorders

 From MayoClinic.com

Causes

Doctors and researchers don't know exactly what causes bipolar disorder. But a variety of biologic, genetic and environmental factors seem to be involved in causing and triggering episodes of this illness.

Evidence indicates that differences in the chemical messengers between nerve cells in the brain (neurotransmitters) occur in people who have bipolar disorder. In many cases people with bipolar disorder may have a genetic disposition for the disorder. The abnormality may be in genes that regulate neurotransmitters.

Factors that may contribute to or trigger episodes of bipolar disorder include drug abuse and stressful or psychologically traumatic events.

Imbalances in neurotransmitter levels are thought to play a role in depression. Neurotransmitters are the chemical messengers that enable nerve cells (neurons) to communicate.  

Risk factors

Bipolar disorder tends to run in families. A family history appears to exist in about 60 percent of cases of bipolar disorder. Researchers are attempting to identify genes that may make people susceptible to bipolar disorder.

When to seek medical advice

People with bipolar disorder often don't recognize how impaired they are when experiencing a mood episode and how greatly the disorder is affecting their lives and the lives of others. Friends, family and primary care physicians are important in recognizing possible signs of bipolar disorder and urging the person to seek professional help.

If a family member or friend shows signs of bipolar disorder, encourage that person to seek the care of a psychiatrist.

 

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This information is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition.
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Last Modified : 03/14/08 07:05 PM